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Ribose/Drug Interactions:- Antidiabetic agentsAntidiabetic agents: Based on secondary sources, adverse reactions to ribose may include symptoms of hypoglycemia.
- Cardiovascular agentsCardiovascular agents: D-ribose (5g/dose, three times daily) in 16 NYHA class III-IV heart failure patients significantly improved ventilatory parameters at anaerobic threshold, along with a 44% Weber class improvement (19). D-ribose has been shown in animal models to improve cardiac energy metabolism and function following ischemia (20).
- Drugs that may lower seizure threshold Drugs that may lower seizure threshold: D-ribose supplementation in a patient with an inherited deficit of adenylosuccinase, severe psychomotor retardation, and epilepsy reduced seizure frequency (18). However, although seizures increased upon attempts to stop ribose supplementation, substitution of D-ribose with D-glucose did not increase seizure activity (18).
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Ribose/Herb/Supplement Interactions:- Antidiabetic agentsAntidiabetic agents: Based on secondary sources, adverse reactions to ribose may include symptoms of hypoglycemia.
- Cardiovascular herbs and supplementsCardiovascular herbs and supplements: D-ribose (5g/dose, three times daily) in 16 NYHA class III-IV heart failure patients significantly improved ventilatory parameters at anaerobic threshold, along with a 44% Weber class improvement (19). D-ribose has been shown in animal models to improve cardiac energy metabolism and function following ischemia (20).
- Herbs/supplements that lower seizure thresholdHerbs/supplements that lower seizure threshold: D-ribose supplementation in a patient with an inherited deficit of adenylosuccinase, severe psychomotor retardation, and epilepsy reduced seizure frequency (18). However, although seizures increased upon attempts to stop ribose supplementation, substitution of D-ribose with D-glucose did not increase seizure activity (18).
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Ribose/Food Interactions:- Insufficient available evidence.
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Ribose/Lab Interactions:- GlucoseGlucose: Based on secondary sources, adverse reactions to ribose may include symptoms of hypoglycemia.
- HypoxanthineHypoxanthine: Physiological effects of ribose have included increased plasma hypoxanthine levels 72 hours after cycle training (11).
- Metabolic markersMetabolic markers: In human evidence, D-ribose supplementation did not have any effects on metabolic markers after high-intensity exercise (21; 8).
- Thallium stress testThallium stress test: Administration of ribose may increase the detection of viable myocardium during the thallium stress test, particularly in patients with severe left ventricular dysfunction (22; 23; 24).
- Uric acidUric acid: According to secondary sources, hyperuricemia or hyperuricosuria may occur during ribose supplementation.
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Copyright © 2011 Natural Standard (www.naturalstandard.com)
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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.
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